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DOI: Liver disease is a major cause of non-HIV morbidity and mortality in this population. Substance abuse accelerates HIV disease and may facilitate progression of liver disease.

This study investigated the relationship between sex differences Miami adult sex cocaine use with liver injury, characterized as hepatic fibrosis. Cocaine use was determined with a validated self-reported questionnaire and confirmed with urine screen.

Fasting blood was used to estimate liver fibrosis using the noninvasive fibrosis-4 FIB-4 index. : Men living with HIV had 1. No ificant association was noted among HIV seronegative Miami adult sex for liver fibrosis by sex differences or cocaine use.

Conclusions: Sex differences and cocaine use appear to affect liver disease among African Americans living with HIV pointing to the importance of identifying at-risk individuals to improve outcomes of liver disease. Grant support.